Impel


Impel Re-Routes Relief for an Innovation in Migraine Treatments


Situation Analysis

Migraines afflict 36 million Americans and rank as the nation’s second leading cause of temporary disability. One of Impel NeuroPharma’s products is a metered-dose medication system called POD (Precision Olfactory Delivery) which dispenses medication to molecular targets in the upper nasal space of the nose. A complementary product is a special spray formulation of dihydroergotamine (DHE), an oral migraine medication called Trudhesa.

Impel planned to bring Trudhesa and POD to market as a combined, prescription-only product as early phase clinical trials found the pairing to provide significantly faster, more complete relief to migraine sufferers than what currently is possible with rival migraine medicines.

The migraine-relief marketplace is crowded with brands and generics. In order for Trudhesa to enter this packed arena and compellingly attract the attention of patients and prescribers, a campaign was developed with the goal of positioning Trudhesa as something new and remarkably better. More precisely, the objective was to present this innovation as an entire rethinking of migraine pain treatment.


Research & Insights


Eighty percent of migraine sufferers have gastroparesis in conjunction with migraine with vomiting prevalent in nearly 30 percent of them (vomiting contributes to the reduced effectiveness of swallowed medications by expelling them from the stomach before they can be absorbed into the bloodstream).

Additionally, most treatments are most effective only if taken before the migraine attack reaches peak intensity. Unfortunately, 70 percent of migraine sufferers wait to take medication until they are sure it really is a migraine attack (often missing the effectiveness window as a result). Furthermore, most treatments provide incomplete relief, and do not quickly end the migraine attack nor prevent it from coming back later that same day because oral treatments tend to target a single mechanism involved in migraine when in actuality, multiple mechanisms are at work.

All of these factors combined led to many patients becoming so frustrated by the seeming lack of effectiveness of the remedy that they eventually gave up and quit taking it. A survey issued by the brand showed that four out of five patients with migraine were looking to try a new treatment.


Strategy


The frustrating plight of migraine patients and the complexity of the disease led to a campaign intended to promote Trudhesa (administered via POD) as a rerouting of migraine relief from the usual starting point of the stomach to a location no other pharmaceutical company was utilizing—the upper nasal space. The program intended to highlight the innovation in this rerouting in how the roadblocks preventing the speedy travel of active ingredients to the brain are completely bypassed.

After creating the campaign slogan “Reroute Migraine Relief,” we developed a series of overlapping educational campaigns for patients and prescribers. The campaigns leveraged data, regulatory, and disease-awareness milestones to share the value of Trudhesa and the need for non-oral options in the treatment of migraine.


Execution & Tactics


To communicate the concept of rerouting migraine relief around biological roadblocks, the campaign commissioned internationally acclaimed portrait artist Ed Fairburn who is known for taking street maps and using the depicted highways and byways as the contours, hatching, cross-hatching, and shading for creating stunning renderings of people’s faces. The maps chosen by Fairburn for this purpose showed intricately winding roads that enabled him to illustrate that migraine is a complex disease that can be difficult to navigate because of its many twists and turns.

“Reroute Migraine Relief” was given its own social channels which were used to promote all elements of the campaign, including the leveraged milestones, as educational websites were created for patients and prescribers featuring a wealth of information about migraine, treatments, and Trudhesa-POD.


Effectiveness & Results


The campaign proved highly effective. During its run, it achieved the following:

• Earned impressions: over 72 million
• Social impressions: in excess of 78,000
• Media interviews: 26
• Website visits: nearly 37,000

Project Visuals 

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